Postpartum Hemorrhage (PPH)

Background: Postpartum hemorrhage (PPH) leads to 25% of all maternal deaths worldwide. It is clinically defined as the loss of more than 500 ml of blood at delivery or 1,000 ml within 24 hours following childbirth. Because of the sporatic incidence and required urgent care, clinical studies of PPH are difficult. Meanwhile, a proper animal model for evaluation of potential therapeutics is lacking.

Model: C-section induced postpartum bleeding

Standard study duration: 8 weeks, upon maturation of pregnancy

Clinical endpoint: Bleeding volume and weight, coagulation tests, blood chemistry…

Features: Human-similar gynecology and childbirth process, female hormone physiology, coagulapathy, drug on-set of action, safety assessment…


For more information about these models, please contact Mr. James Song, mailto:james.song@prisysbiotech.com

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