Prostatic Hyperplasia/Cancer
Background:Benign prostatic
hyperplasia - also called BPH - is a condition in men in which the prostate gland
is enlarged and not cancerous. Benign prostatic hyperplasia is also called
benign prostatic hypertrophy or benign prostatic obstruction.
Prostate cancer can affect any part of the
prostate, but it is usually the lateral lobes, the sides of the prostate, that
are affected. In advanced cases, prostate cancer can spread to the bones, but
usually only travels to areas within the pelvis.
Model: Spontaneous
prostatic hyperplasia in aged monkey by elevated PSA
Standard study duration: 6-12 months
Clinical endpoint: Blood PSA
levels; B-ultrasound; Biopsy, histology, and IHC; Targets and biomarkers; Features: BPH, carcinogenesis and the experimental therapeutics,
Recurrence following prostatectomy, PSA targeted therapy
Status: Open for Co-development