Pain

Background: The World Health Organization (WHO) released a preliminary version of the 11th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-11) in June 2018.1 The ICD-11 is scheduled to go into effect in the year 2022. Among the major innovations introduced in the update of this fundamental, now fully electronic, reference for health statistics is a systematic classification of clinical conditions associated with chronic pain. The classification was developed by an interdisciplinary task force of the International Association for the Study of Pain (IASP) to remedy gaps and errors in the prior version, ICD-10.2,3 The new list of diagnostic codes covers the most common painful clinical entities and divides them into subgroups defined by etiology or affected organ system. The classification further includes a subgroup of conditions primarily characterized by pain whose underlying cause is incompletely understood. With the implementation of this systematic classification, ICD-11 takes a decisive step to better reflect the significance of chronic pain as a health problem of enormous epidemiological, economic, and sociological impact.

Model: Nerve constriction induced neuropathic pain, post-surgery pain, chemical induced pain, chronic pain, Chemo-therapy induced neuropathic pain

Standard study duration: 4-8 weeksClinical endpoint:

•     Activity index

•     Sleeping assessment

•     Food/water intake

•     Hyperalgesia tests(Thermal/electrical/mechanical)

•     ECG/EMG/EEG

•     motor activity

•     nerve conduction

Features: Various pain models according to classification, high incidence, enhanced monitoring/husbandry, multiple pain assessment methods

 

For more information about these models, please contact Mr. James Song, mailto:james.song@prisysbiotech.com
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